Prof. Dr. med. Klemens Raile

seit 11.2022
Chefarzt, Klinik für Kinder- und Jugendmedizin, Klinikum Neukölln, Berlin

2017 - 2022
Kommissarische Klinikleitung, Klinik für Pädiatrie mit Schwerpunkt Endokrinologie und Diabetologie, Charité - Universitätsmedizin Berlin

2015 - 2017
Stellvertretende Klinikleitung, Klinik für Pädiatrie mit Schwerpunkt Endokrinologie und Diabetologie, Charité - Universitätsmedizin Berlin

2008 - 2014
Oberarzt der Klinik für Pädiatrie mit dem Schwerpunkt Endokrinologie, Gastroenterologie und Stoffwechsel (vormals Klinik für Allgemeinpädiatrie), Charité - Universitätsmedizin Berlin

2005 - 2008
Funktionsoberarzt Diabetologie, Leiter pädiatrische Diabetologie, Interdisziplinäres SPZ, Charité - Universitätsmedizin Berlin    

2004 - 2005
Weiterbildung Pädiatrische Endokrinologie und Diabetologie, Hintergrunddienste neonatales Screeninglabor, Universitätskinderklinik, Leipzig

2000 - 2004
Arzt in Weiterbildung und Forschungsstipendium, klinische Schwerpunkte: pädiatrische Intensivmedizin und pädiatrische Endokrinologie und Diabetologie, Universitätskinderklinik, Leipzig

1996 - 2000
Arzt in Weiterbildung, Schwerpunkte neonatologische Intensivstation (NIPS) und pädiatrische Endokrinologie, Dr. v. Haunersches Kinderspital – LMU-München  

1994 -1996
Arzt im Praktikum, Pädiatrie, Kinderklinik - Klinikum Augsburg

1995
Promotion

1987 -1994
Studium der Humanmedizin an der technischen Universität München

Aktuelle Publikationsliste auf PubMed

Erst- und Letztautorschaften

Braune K, Boss K, Schmidt-Herzel J, Gajewska KA, Thieffry A, Schulze L, Posern B, Raile K. Shaping Workflows in Digital and Remote Diabetes Care During the COVID-19 Pandemic: A Service Design Approach. JMIR Mhealth Uhealth. 2020 Online ahead of print. IF 4.31

Raile K, Boss K, Braune K, Heinrich-Rohr M. Versorgung von Kindern und Jugendlichen mit Typ-1-Diabetes: Lösungen für technische und psychosoziale Herausforderungen. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63:856-863. IF 1.05

Braune K, O'Donnell S, Cleal B, Lewis D, Tappe A, Willaing I, Hauck B, Raile K. Real-World Use of Do-It-Yourself Artificial Pancreas Systems in Children and Adolescents With Type 1 Diabetes: Online Survey and Analysis of Self-Reported Clinical Outcomes. JMIR Mhealth Uhealth. 2019 7:e14087. IF 4.31 

Gong M, Yu Y, Liang L, Vuralli D, Froehler S, Kuehnen P, Du Bois P, Zhang J, Cao A, Liu Y, Hussain K, Fielitz J, Jia S, Chen W, Raile K. HDAC4 mutations cause diabetes and induce β-cell FoxO1 nuclear exclusion. Mol Genet Genomic Med. 2019. 7:e602. IF:2.0

Neumann U, Bührer C, Blankenstein O, Kühnen P, Raile K. Primary sulphonylurea therapy in a newborn with transient neonatal diabetes attributable to a paternal uniparental disomy 6q24 (UPD6). Diabetes Obes Metab. 2018, 20:474-475. IF:5.9

Raile K, Schober E, Konrad K, Thon A, Grulich-Henn J, Meissner T, Wolfle J, Scheuing N, Holl RW. Treatment of young patients with HNF1A mutations (HNF1A-MODY). Diab Med. 2015 32:526-530. IF:4.36

Simaite D, Kofent J, Gong M, Rüschendorf F, Jia S, Arn P, Bentler K, Ellaway C, Kühnen P, Hoffmann GF, Blau N, Spagnoli FM, Hübner N, Raile K. Recessive mutations in PCBD1 cause a new type of early-onset diabetes. Diabetes. 2014 PMID:24848070. IF:7.72

Becker M, Galler A, Raile K. Meglitinide Analogues in Adolescent Patients With
HNF1A-MODY (MODY 3). Pediatrics. 2014 Mar;133(3):e775-9. PMID: 24567025. IF:5.2

Gong M, Simaite D, Kühnen P, Heldmann M, Spagnoli F, Blankenstein O, Hübner N,
Hussain K, Raile K. Two novel GATA6 mutations cause childhood-onset diabetes mellitus, pancreas malformation and congenital heart disease. Horm Res Paediatr. 2013;79(4):250-6. PMID: 23635550. IF: 2.17

Galler A, Lindau M, Ernert A, Thalemann R, Raile K. Associations between media consumption habits, physical activity, socioeconomic status, and glycemic control in children, adolescents, and young adults with type 1 diabetes. Diabetes Care.
2011 Nov;34(11):2356-9. PMID:21926289 IF: 16.02

Raile K, O'Connell M, Galler A, Werther G, Kühnen P, Krude H, Blankenstein O. Diabetes caused by insulin gene (INS) deletion: clinical characteristics of homozygous and heterozygous individuals. Eur J Endocrinol. 2011 Aug;165(2):255-60. doi: 10.1530/EJE-11-0208. PMID:21566073. IF: 5.3

Raile K, Klopocki E, Holder M, Wessel T, Galler A, Deiss D, Müller D, Riebel T, Horn D, Maringa M, Weber J, Ullmann R, Grüters A. Expanded clinical spectrum in hepatocyte nuclear factor 1b-maturity-onset diabetes of the young. J Clin Endocrinol Metab. 2009 Jul;94(7):2658-64. PMID: 19417042. IF: 6.3

Raile K, Klopocki E, Wessel T, Deiss D, Horn D, Müller D, Ullmann R, Grüters A. HNF1B abnormality (mature-onset diabetes of the young 5) in children and adolescents: high prevalence in autoantibody-negative type 1 diabetes with kidney defects. Diabetes Care. 2008 Nov;31(11):e83. doi: 10.2337/dc08-0920. PMID: 18955710. IF: 16.02

Raile K, Galler A, Hofer S, Herbst A, Dunstheimer D, Busch P, Holl RW. Diabetic nephropathy in 27,805 children, adolescents, and adults with type 1 diabetes: effect of diabetes duration, A1C, hypertension, dyslipidemia, diabetes onset, and sex. Diabetes Care. 2007 Oct;30(10):2523-8. Epub 2007 Jul 13. PMID: 17630266. IF: 16.02 

Däublin G, Lorenz-Depiereux B, Strom TM, Blankenstein O, Raile K. Early
glibenclamide treatment in a clinical newborn with KCNJ11gene mutation. Diabetes Care. 2007 Oct;30(10):e104. PMID: 17901525. IF: 16.02

Raile K, Klammt J, Garten A, Laue S, Blüher M, Kralisch S, Klöting N, Kiess W. Glucose regulates expression of the nerve growth factor (NGF) receptors TrkA and p75NTR in rat islets and INS-1E beta-cells. Regul Pept. 2006 Jul 15;135(1-2):30-8. PMID: 16644033. IF:2.0 (2016)

Raile K, Klammt J, Schneider A, Keller A, Laue S, Smith R, Pfäffle R, Kratzsch J, Keller E, Kiess W. Clinical and functional characteristics of the human Arg59Ter insulin-like growth factor i receptor (IGF1R) mutation: implications for a gene dosage effect of the human IGF1R. J Clin Endocrinol Metab. 2006 Jun;91(6):2264-71. PMID: 16569742. IF:6.3

Raile K, Klammt J, Laue S, Garten A, Blüher M, Kralisch S, Klöting N, Kiess W. Glucose concentration and AMP-dependent kinase activation regulate expression of insulin receptor family members in rat islets and INS-1E beta cells. Diabetologia. 2005 Sep;48(9):1798-809. PMID: 16052330. IF:7.52 

Raile K, Stobbe H, Tröbs RB, Kiess W, Pfäffle R. A new heterozygous mutation of the FOXL2 gene is associated with a large ovarian cyst and ovarian dysfunction in an adolescent girl with blepharophimosis/ptosis/epicanthus inversus syndrome. Eur J Endocrinol. 2005 Sep;153(3):353-8. PMID: 16131596. IF: 5.3

Raile K, Hille R, Laue S, Schulz A, Pfeifer G, Horn F, Kiess W. Insulin-like  growth factor I (IGF-I) stimulates proliferation but also increases caspase-3 activity, Annexin-V binding, and DNA-fragmentation in human MG63 osteosarcoma cells: co-activation of pro- and anti-apoptotic pathways by IGF-I. Horm Metab Res. 2003 Nov-Dec;35(11-12):786-93. PMID: 14710359. IF 2.57

Raile K, Berthold A, Banning U, Horn F, Pfeiffer G, Kiess W. IGFs, basic FGF, and glucose modulate proliferation and apoptosis induced by IFNgamma but not by IL-1beta in rat INS-1E beta-cells. Horm Metab Res. 2003 Jul;35(7):407-14. PMID: 12931271. IF: 2.57

Raile K, Noelle V, Landgraf R, Schwarz HP. Weight in adolescents with type 1 diabetes mellitus during continuous subcutaneous insulin infusion (CSII) therapy. J Pediatr Endocrinol Metab. 2002 May;15(5):607-12. PMID: 12014519. IF: 1.28

Raile K, Noelle V, Landgraf R, Schwarz HP. Insulin antibodies are associated with lipoatrophy but also with lipohypertrophy in children and adolescents with type 1 diabetes. Exp Clin Endocrinol Diabetes. 2001;109(8):393-6. PMID:11748486. IF: 2.10

Raile K, Kapellen T, Schweiger A, Hunkert F, Nietzschmann U, Dost A, Kiess W. Physical activity and competitive sports in children and adolescents with type 1 diabetes. Diabetes Care. 1999 Nov;22(11):1904-5. PMID: 10546027. IF: 16.02

Raile K, Simbruner G. The Hemocue B glucose analyser and neonatal blood glucose monitoring. Ann Clin Biochem. 1998 35:329-30; author reply 332-3. PMID: 9547914. IF: 2.06

Raile K, Höflich A, Kessler U, Yang Y, Pfuender M, Blum WF, Kolb H, Schwarz HP, Kiess W. Human osteosarcoma (U-2 OS) cells express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose-6-phosphate  (IGF-II/M6P) receptors and synthesize IGF-II: autocrine growth stimulation by IGF-II via the IGF-I receptor. J Cell Physiol. 1994 Jun;159(3):531-41. PMID: 8188767. IF: 5.55

Koautorschaften

Hackl L, Bonfig W, Pozza SB, Lanzinger S, Treptau N, Raile K, Elpel U, Ludwig KH, Buchal G, Holl RW; DPV registry. Size matters - influence of center size on quality of diabetes control in children and adolescents with type 1 diabetes: A longitudinal analysis of the DPV cohort. Pediatr Diabetes. 2021 Nov 14. doi: 10.1111/pedi.13283. Online ahead of print. PMID:34779099 

Braune K, Lal RA, Petruželková L, Scheiner G, Winterdijk P, Schmidt S, Raimond L, Hood KK, Riddell MC, Skinner TC, Raile K, Hussain S; OPEN International Healthcare Professional Network and OPEN Legal Advisory Group. Open-source automated insulin delivery: international consensus statement and practical guidance for health-care professionals. Lancet Diabetes Endocrinol. 2021 Nov 12:S2213-8587(21). Online ahead of print. IF 32.07

Knoll C, Peacock S, Wäldchen M, Cooper D, Aulakh SK, Raile K, Hussain S, Braune K. Real-world Evidence on Clinical Outcomes of People with Type 1 Diabetes Using Open-Source and Commercial Automated Insulin Dosing Systems: A Systematic Review. Diabet Med. 2021 Nov 12:e14741. Online ahead of print. IF 4.36

Albanese-O'Neill A, Grimsmann JM, Svensson AM, Miller KM, Raile K, Akesson K, Calhoun P, Biesenbach B, Eeg-Olofsson K, Holl RW, Maahs DM, Hanas R. Changes in HbA1c Between 2011 and 2017 in Germany/Austria, Sweden, and the United States: A Lifespan Perspective. Diabetes Technol Ther. 2021 Oct 11. Online ahead of print. IF 6.20

Mönkemöller K, Kamrath C, Hammersen J, Biester T, Warncke K, Pappa A, Fink K, Raile K, Rohrer TR, Holl RW; DPV Initiative. [Is it possible to prevent diabetic ketoacidosis at diagnosis of pediatric type 1 diabetes? Lessons from the COVID-19 pandemic] Monatsschr Kinderheilkd. 2021. 8:1-8.  Online ahead of print. IF: 0.25

Bowman P, Mathews F, Barbetti F, Shepherd MH, Sanchez J, Piccini B, Beltrand J, Letourneau-Freiberg LR, Polak M, Greeley SAW, Rawlins E, Babiker T, Thomas NJ, De Franco E, Ellard S, Flanagan SE, Hattersley AT; Neonatal Diabetes International Collaborative Group (…, Raile K, .. 1/36). Long-term Follow-up of Glycemic and Neurological Outcomes in an International Series of Patients With Sulfonylurea-Treated ABCC8 Permanent Neonatal Diabetes. Diabetes Care. 2021 44(1):35-42. IF 16.02

Su X, Feng Y, Rahman SA, Wu S, Li G, Rüschendorf F, Zhao L, Cui H, Liang J, Fang L, Hu H, Froehler S, Yu Y, Patone G, Hummel O, Chen Q, Raile K, Luft FC, Bähring S, Hussain K, Chen W, Zhang J, Gong M.  Phosphatidylinositol 4-kinase β mutations cause nonsyndromic sensorineural deafness and inner ear malformation. J Genet Genomics. 2020. 47:618-626. IF 5.1

Braune K, Wäldchen M, Raile K, Hahn S, Ubben T, Römer S, Hoeber D, Reibel NJ, Launspach M, Blankenstein O, Bührer C Open-Source Technology for Real-Time Continuous Glucose Monitoring in the Neonatal Intensive Care Unit: Case Study in a Neonate With Transient Congenital Hyperinsulinism. J Med Internet Res. 2020. 22:e21770.  IF 5.03

Jasser-Nitsche H, Bechtold-Dalla Pozza S, Binder E, Bollow E, Heidtmann B, Lee-Barkley YH, Raile K, de Sousa G, Schramm U, Holl RW. Comorbidity of inflammatory bowel disease in children and adolescents with type 1 diabetes. Acta Paediatr. 2020, Epub ahead of print. IF 2.1

O'Donnell S, Lewis D, Marchante Fernández M, Wäldchen M, Cleal B, Skinner T, Raile K, Tappe A, Ubben T, Willaing I, Hauck B, Wolf S, Braune K. Evidence on User-Led Innovation in Diabetes Technology (The OPEN Project): Protocol for a Mixed Methods Study. JMIR Res Protoc. 2019 19;8(11):e15368 IF 1.25.

Binger KJ, Neukam M, Tattikota SG, Qadri F, Puchkov D, Willmes DM, Wurmsee S, Geisberger S, Dechend R, Raile K, Kurth T, Nguyen G, Poy MN, Solimena M, Muller DN, Birkenfeld AL. Atp6ap2- deletion causes extensive vacuolation that consumes the insulin content of pancreatic β cells. Proc Natl Acad Sci U S A. 2019 116:19983-19988. IF 9.41

Neu A, Bürger-Büsing J, Danne T, Dost A, Holder M, Holl RW, Holterhus PM, Kapellen T, Karges B, Kordonouri O, Lange K, Müller S, Raile K, Schweizer R, Sengbusch SV, Stachow R, Wagner V, Wiegand S, Ziegler R. Diagnosis, Therapy and Follow-up of Diabetes Mellitus in Children and Adolescents. Exp Clin Endocrinol Diabetes. 2019 127:341-352. IF 2.10

Jacobi SF, Khajavi N, Kleinau G, Teumer A, Scheerer P, Homuth G, Völzke H, Wiegand S, Kühnen P, Krude H, Gong M, Raile K, Biebermann H. Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes. Diabetes Obes Metab. 2019 21:1168-1176. IF 5.90

Warncke K, Kummer S, Raile K, Grulich-Henn J, Woelfle J, Steichen E, Prinz N, Holl RW. Frequency and Characteristics of MODY 1 (HNF4A Mutation) and MODY 5 (HNF1B Mutation): Analysis From the DPV Database. J Clin Endocrinol Metab. 2019 104:845-855. IF 6.31

Hattersley AT, Greeley SAW, Polak M, Rubio-Cabezas O, Njølstad PR, Mlynarski W, Castano L, Carlsson A, Raile K, Chi DV, Ellard S, Craig ME. ISPAD Clinical Practice Consensus Guidelines 2018: The diagnosis and management of monogenic diabetes in children and adolescents. Pediatr Diabetes. 2018 27:47-63. IF 3.13

Bechtold SM, Rohrer TR, Raile K, Hofer S, Thon A, Boettcher C, Konrad K, Pozza RD, Bollow E, Holl RW. Diabetes mellitus in pediatric solid organ recipients without and with cystic fibrosis: An analysis from the German-Austrian diabetes database (Diabetes Patienten Verlaufsdokumentation). Pediatr Diabetes. 2018;19:1191-1197. IF 3.13

Mühlhaus J, Dinter J, Jyrch S, Teumer A, Jacobi SF, Homuth G, Kühnen P, Wiegand S, Grüters A, Völzke H, Raile K, Kleinau G, Krude H, Biebermann H. Investigation of Naturally Occurring Single-Nucleotide Variants in Human TAAR1. Front Pharmacol. 2017 8:807. 

Hörtenhuber T, Kiess W, Fröhlich-Reiterer E, Raile K, Stachow R, Bollow E, Rami-Merhar B, Holl RW; DPV-Wiss Study Group. Asthma in children and adolescents with type 1 diabetes in Germany and Austria: Frequency and metabolic control. Pediatr Diabetes. 2018, 19:727-732. IF 3.13

Pacaud D, Hermann JM, Karges B, Rosenbauer J, Danne T, Dürr R, Herbst A, Lindauer S, Müther S, Pötzsch S, Raile K, Witsch M, Holl RW; DPV Initiative. Risk of recurrent severe hypoglycemia remains associated with a past history of severe hypoglycemia up to 4 years: Results from a large prospective contemporary pediatric cohort of the DPV initiative. Pediatr Diabetes. 2018, 19:493-500. IF:4.23

Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium (…, Raile K, …), Todd JA, Wallace C, Concannon P, Rich SS. Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nat Genet. 2015 Apr;47(4):381-6. IF: 27.6

Hofer SE, Raile K, Frohlich-Reiterer E, Kapellen T, Dost A, Rosenbauer J, Grulich-Henn J, Holl RW, Austrian/German Diabetes Patienten Verlaufsdokumentation DPVI, German Competence Network for Diabetes M: Tracking of metabolic control from childhood to young adulthood in type 1 diabetes. J Pediatr. 2014 165:956-961 IF: 3.70

Dost A, Molz E, Krebs A, Bechtold S, Kapellen T, Rohrer T, Raile K, Fritsch M, Schwab KO, Holl R: Pulse pressure in children and adolescents with type 1 diabetes mellitus in Germany and Austria. Pediatr Diabet 2014 15:236-243 IF: 3.13

Kühnen P, Matthae R, Arya V, Hauptmann K, Rothe K, Wächter S, Singer M, Mohnike W, Eberhard T, Raile K, Lauffer LM, Iakoubov R, Hussain K, Blankenstein O. Occurrence of giant focal forms of congenital hyperinsulinism with incorrect visualization by 18 F DOPA-PET/CT scanning. Clin Endocrinol. 2014 PMID:24750227. IF: 3.38

Heinzerling L, Raile K, Rochlitz H, Zuberbier T, Worm M. Insulin allergy: clinical manifestations and management strategies. Allergy. 2008 Feb;63(2):148-55. PMID: 18186805. IF: 8.71

Bechtold S, Blaschek A, Raile K, Dost A, Freiberg C, Askenas M, Fröhlich-Reiterer E, Molz E, Holl RW. Higher relative risk for multiple sclerosis in a pediatric and adolescent diabetic population: analysis from DPV database. Diabetes Care. 2014 Jan;37(1):96-101. PMID: 23990514. IF: 16.02

Holterhus PM, Bokelmann J, Riepe F, Heidtmann B, Wagner V, Rami-Merhar B, Kapellen T, Raile K, Quester W, Holl RW; German/Austrian DPV-Initiative and the German Pediatric CSII Working Group. Predicting the optimal basal insulin infusion pattern in children and adolescents on insulin pumps. Diabetes Care. 2013 Jun;36(6):1507-11. PMID: 23404300 IF:16.02

Kühnen P, Marquard J, Ernert A, Meissner T, Raile K, Wannenmacher G, Blankenstein O. Long-term lanreotide treatment in six patients with congenital hyperinsulinism. Horm Res Paediatr. 2012;78(2):106-12. PMID: 22907123.     IF: 2.52

Ludvigsson J, Krisky D, Casas R, Battelino T, Castaño L, Greening J, Kordonouri O, Otonkoski T, Pozzilli P, Robert JJ, Veeze HJ, Palmer J, Samuelsson U, Elding Larsson H, Åman J, Kärdell G, Neiderud Helsingborg J, Lundström G, Albinsson E, Carlsson A, Nordvall M, Fors H, Arvidsson CG, Edvardson S, Hanås R, Larsson K, Rathsman B, Forsgren H, Desaix H, Forsander G, Nilsson NÖ, Åkesson CG, Keskinen P, Veijola R, Talvitie T, Raile K, Kapellen T, Burger W, Neu A, Engelsberger I, Heidtmann B, Bechtold S, Leslie D, Chiarelli F, Cicognani A, Chiumello G, Cerutti F, Zuccotti GV, Gomez Gila A, Rica I, Barrio R, Clemente M, López Garcia MJ, Rodriguez M, Gonzalez I, Lopez JP, Oyarzabal M, Reeser HM, Nuboer R, Stouthart P, Bratina N, Bratanic N, de Kerdanet M, Weill J, Ser N, Barat P, Bertrand AM, Carel JC, Reynaud R, Coutant R, Baron S. GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus.  N Engl J Med. 2012;366(5):433-42. IF: 74.70

Galler A, Haberland H, Näke A, Hofer S, Holder M, Raile K, Holl RW; German Federal Ministry for Education and Research BMBF Competence Network of Diabetes Mellitus. Natural course of untreated microalbuminuria in children and adolescents with type 1 diabetes and the importance of diabetes duration and immigrant status: longitudinal analysis from the prospective nationwide German and Austrian diabetes survey DPV. Eur J Endocrinol. 2012 Mar;166(3):493-501. PMID: 22199141. IF: 5.31

Ludwig-Seibold CU, Holder M, Rami B, Raile K, Heidtmann B, Holl RW; DPV Science Initiative; German Working Group for insulin pump treatment in pediatric patients; German BMBF Competence Network Diabetes. Continuous glucose monitoring in children, adolescents, and adults with type 1 diabetes mellitus: analysis from the prospective DPV diabetes documentation and quality management system from Germany and Austria. 
Pediatr Diabetes. 2012 Feb;13(1):12-4. PMID: 22128781. IF: 3.13

Hammes HP, Kerner W, Hofer S, Kordonouri O, Raile K, Holl RW; DPV-Wiss Study Group. Diabetic retinopathy in type 1 diabetes-a contemporary analysis of 8,784 patients. Diabetologia. 2011 Aug;54(8):1977-84. PMID: 21638132. IF: 7.52

Kuehnen P, Laubner K, Raile K, Schöfl C, Jakob F, Pilz I, Päth G, Seufert J. Protein phosphatase 1 (PP-1)-dependent inhibition of insulin secretion by leptin in INS-1 pancreatic β-cells and human pancreatic islets. Endocrinology. 2011 May;152(5):1800-8. PMID: 21427225. IF: 3.9

Awa WL, Thon A, Raile K, Grulich-Henn J, Meissner T, Schober E, Holl RW; DPV-Wiss. Study Group. Genetic and clinical characteristics of patients with HNF1A gene variations from the German-Austrian DPV database. Eur J Endocrinol. 2011 Apr;164(4):513-20. PMID:  1224407. IF:5.31

Weber SC, Uhlenberg B, Raile K, Querfeld U, Müller D. Polyoma virus-associated progressive multifocal leukoencephalopathy after renal transplantation: regression following withdrawal of mycophenolate mofetil. Pediatr 
Transplant. 2011 Mar;15(2):E19-24. PMID: 20880091. 
IF: 1.43

Grulich-Henn J, Wagner V, Thon A, Schober E, Marg W, Kapellen TM, Haberland H, Raile K, Ellard S, Flanagan SE, Hattersley AT, Holl RW. Entities and frequency of neonatal diabetes: data from the diabetes documentation and quality management system (DPV). Diabet Med. 2010 Jun;27(6):709-12. PMID: 20546293. IF: 3.08

Garin I, Edghill EL, Akerman I, Rubio-Cabezas O, Rica I, Locke JM, Maestro MA, Alshaikh A, Bundak R, del Castillo G, Deeb A, Deiss D, Fernandez JM, Godbole K, Hussain K, O'Connell M, Klupa T, Kolouskova S, Mohsin F, Perlman K, Sumnik Z, Rial JM, Ugarte E, Vasanthi T; Neonatal Diabetes International Group, JohnstoneK, Flanagan SE, Martínez R, Castaño C, Patch AM, Fernández-Rebollo E, Raile K, Morgan N, Harries LW, Castaño L, Ellard S, Ferrer J, Perez de Nanclares G, Hattersley AT. Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3105-10. PMID: 20133622 IF: 9.4

Hofer SE, Heidtmann B, Raile K, Fröhlich-Reiterer E, Lilienthal E, Berghaeuser MA, Holl RW; DPV-Science-Initiative and the German working group for insulin pump treatment in pediatric patients. Discontinuation of insulin pump treatment in children, adolescents, and young adults. A multicenter analysis based on the DPV database in Germany and Austria. Pediatr Diabetes. 2010 Mar;11(2):116-21. PMID: 19566740. IF: 3.13

Wiegand S, Raile K, Reinehr T, Hofer S, Näke A, Rabl W, Holl RW; DPV-Wiss Study Group. Daily insulin requirement of children and adolescents with type 1 diabetes: effect of age, gender, body mass index and mode of therapy. Eur J Endocrinol. 2008 Apr;158(4):543-9. PMID: 18362302. IF: 5.31

Knerr I, Dost A, Lepler R, Raile K, Schober E, Rascher W, Holl RW; Diabetes Data Acquisition System for Prospective Surveillance (DPV) Scientific Initiative Germany and Austria. Tracking and prediction of arterial blood pressure from childhood to young adulthood in 868 patients with type 1 diabetes: a multicenter longitudinal survey in Germany and Austria. Diabetes Care. 2008 Apr; 31(4):726-7. PMID: 18184906. IF: 16.02

Rohrer T, Stierkorb E, Heger S, Karges B, Raile K, Schwab KO, Holl RW; Diabetes-Patienten-Verlaufsdaten (DPV) Initiative. Delayed pubertal onset and development in German children and adolescents with type 1 diabetes: cross-sectional analysis of recent data from the DPV diabetes documentation and quality management system. Eur J Endocrinol. 2007 Nov;157(5):647-53. PMID: 17984245. IF: 5.31

Kratzsch J, Knerr I, Galler A, Kapellen T, Raile K, Körner A, Thiery J, Dötsch J, Kiess W. Metabolic decompensation in children with type 1 diabetes mellitus associated with increased serum levels of the soluble leptin receptor. Eur J Endocrinol. 2006 Oct;155(4):609-14. PMID: 16990661. IF: 5.31

Bechtold S, Dirlenbach I, Raile K, Noelle V, Bonfig W, Schwarz HP. Early manifestation of type 1 diabetes in children is a risk factor for changed bone geometry: data using peripheral quantitative computed tomography. Pediatrics.2006 Sep;118(3):e627-34. PMID: 16908617. IF: 4.47

Seifert W, Holder-Espinasse M, Spranger S, Hoeltzenbein M, Rossier E, Dollfus H, Lacombe D, Verloes A, Chrzanowska KH, Maegawa GH, Chitayat D, Kotzot D, Huhle D, Meinecke P, Albrecht B, Mathijssen I, Leheup B, Raile K, Hennies HC, Horn D. Mutational spectrum of COH1 and clinical heterogeneity in Cohen syndrome. J Med Genet. 2006 May;43(5):e22. PMID: 16648375 IF:4.94

Kiess W, Kratzsch J, Keller E, Schneider A, Raile K, Klammt J, Seidel B, Garten A, Schmidt H, Pfäffle R. Clinical examples of disturbed IGF signaling: intrauterine and postnatal growth retardation due to mutations of the insulin-like growth factor I receptor (IGF-IR) gene. Rev Endocr Metab Disord. 2005 Aug;6(3):183-7. PMID: 16151622. IF:6.51

Kiess W, Böttner A, Blüher S, Raile K, Galler A, Kapellen TM. Type 2 diabetes mellitus in children and adolescents--the beginning of a renal catastrophe? Nephrol Dial Transplant. 2004 Nov;19(11):2693-6. PMID: 15385634 IF:4.53

Kiess W, Raile K, Galler A, Kapellen T. Insulin detemir offers improved glycemic control compared with NPH insulin in people with type 1 diabetes. Diabetes Care. 2004 Oct;27(10):2567-8. PMID: 15451944. IF:16.02

Kapellen TM, Böttner A, Galler A, Raile K, Nietzschmann U, Kiess W. [Treatment of adolescents with type 2 diabetes]. Klin Padiatr. 2004 216(2):57-61. PMID: 15106074. IF:0.55

Abuzzahab MJ, Schneider A, Goddard A, Grigorescu F, Lautier C, Keller E, Kiess W, Klammt J, Kratzsch J, Osgood D, Pfäffle R, Raile K, Seidel B, Smith RJ, Chernausek SD; Intrauterine Growth Retardation (IUGR) Study Group. IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation. N Engl J Med. 2003 Dec 4;349(23):2211-22. PMID: 14657428. IF: 74.70

Bonfig W, Bittmann I, Bechtold S, Kammer B, Noelle V, Arleth S, Raile K, Schwarz HP. Virilising adrenocortical tumours in children. Eur J Pediatr. 2003 Sep;162(9):623-8. PMID: 12811553. IF:2.30 

Kiess W, Böttner A, Blüher S, Raile K, Seidel B, Kapellen T, Keller E, Kratzsch J.  Pharmacoeconomics of obesity management in childhood and adolescence. Expert Opin Pharmacother. 2003 Sep;4(9):1471-7. PMID: 12943476. IF:2.88

Kiess W, Böttner A, Raile K, Kapellen T, Müller G, Galler A, Paschke R, Wabitsch M. Type 2 diabetes mellitus in children and adolescents: a review from a European perspective. Horm Res. 2003;59 Suppl 1:77-84. PMID: 12566725. IF:2.17

Kapellen TM, Heim K, Nietzschmann U, Galler A, Raile K, Kiess W. Changes in pediatric diabetes care throughout a 30-yr period at one institution for pediatric diabetology in Germany. Pediatr Diabetes. 2002 Jun;3(2):70-3. PMID: 15016159. IF:3.14

Gallaher BW, Hille R, Raile K, Kiess W. Apoptosis: live or die--hard work either way! Horm Metab Res. 2001 Sep;33(9):511-9. PMID: 11561209. IF:2.56

Kiess W, Galler A, Reich A, Müller G, Kapellen T, Deutscher J, Raile K, Kratzsch J. Clinical aspects of obesity in childhood and adolescence. Obes Rev. 2001 Feb;2(1):29-36. PMID: 12119634. IF: 8.19

Kiess W, Reich A, Müller G, Galler A, Kapellen T, Raile K, Böttner A, Seidel  B, Kratzsch J. Obesity in childhood and adolescence: clinical diagnosis and management. J Pediatr Endocrinol Metab. 2001;14 Suppl 6:1431-40. PMID: 11837496. IF: 1.28

Kiess W, Galler A, Schmidt A, Nietzschmann U, Neu A, Raile K, Kapellen T. Fathers of children with diabetes mellitus and their role in coping strategies in the family. J Pediatr Endocrinol Metab. 2001;14 Suppl 1:639-43. PMID:11393557. IF:1.28

Kiess W, Kapellen T, Siebler T, Deutscher J, Raile K, Dost A, Meyer K, Nietzchmann U. Practical aspects of managing preschool children with type 1 diabetes. Acta Paediatr Suppl. 1998 Oct;425:67-71. PMID: 9822197. IF:2.11

Buchkapitel

Raile K, Bechtold-Dalla-Pozza S. Kap 14.6 Varianten der Geschlechtsentwicklung und 14.7 Adrenogenitales Syndrom. In: Genzel-Boroviczény O und Nußbaum C (Hrsg): Checkliste Neonatologie, 7.Aufl. 2022, ISBN: 9783132442252

Raile K, Blankenstein O. Kap 14.6 Erkrankungen der Schilddrüse. In: Genzel-Boroviczény O und Nußbaum C (Hrsg): Checkliste Neonatologie, 7.Aufl. 2022, ISBN: 9783132442252

Raile K, Mihatsch W. Kap. 5.3 Hypoglykämie und 5.4 Hyperglykämie und neonataler Diabetes. In: Genzel-Boroviczény O und Nußbaum C (Hrsg): Checkliste Neonatologie, 7.Aufl. 2022, ISBN: 9783132442252

Raile K und Kordonouri O: Diabetesformen bei Kindern und Jugendlichen. In: Hiort O, Danne T, Wabitsch M. Pädiatrische Endokrinologie und Diabetologie, (Springer Reference Medizin 2. Aufl. 2019) ISBN: 978-3662592892. 

Raile K, Bechtold-DallaPozza S: Angeborene Störungen und Besonderheiten in der Pädiatrie (Diabetes mellitus). In: Diederich S, Feldkamp J, Grußendorf M und Reincke M (Hrsg): Referenz Endokrinologie und Diabetologie, Thieme Verlag, Heidelberg (1. Aufl. 2020) ISBN: 9783132408272.

Raile K, Bechtold-DallaPozza S: Kap. 14 Endokrinologie und Stoffwechsel; in: Genzel-Boroviczény O, Roos R (Hrsg): Checkliste Neonatologie, Thieme Verlag, Heidelberg (2018)  ISBN 9783131250552. (Auflagen 1-6).

Raile K, Kapellen TM: Diabetische Ketoazidose. In: Kiess W, Merkenschlager A, Pfäffle R, Siekmeyer W: Therapie in der Kinder- und Jugendmedizin. Urban & Fischer Verlag, München (2007) 346-351. ISBN 978-3-437-23200-8. 

Raile K, Kapellen TM Diabetes mellitus. In: Kiess W, Merkenschlager A, Pfäffle R, Siekmeyer W: Therapie in der Kinder- und Jugendmedizin. Urban & Fischer Verlag, München (2007); 571-583 ISBN 978-3-437-23200-8.

Raile K, Kapellen T, Kiess W: Diabetes mellitus - Kindes- und Jugendalter. Kapitel N1.3-1 bis N1.3-16. In: Berger M, Domschke W, Hohenberger W, Meinertz T, Possinger K, Reinhardt D: Therapie-Handbuch. Urban & Fischer Verlag, München, Jena (2007); 1-13 ISBN 3-437-22106-X 5. Auflage.

Kapellen TM, Galler A, Raile K, Kiess W: Complications and consequences. in: Chiarelli F, Dahl-Jorgensen K, Kiess W(Hrsg.): Diabetes mellitus in childhood and adolescence., Karger Verlag, Basel (2005); 329-346,ISBN 3-8055-7766-4

Raile K: Sports and physical activity in Children and Adolescents with Type 1 Diabetes mellitus. in: Chiarelli F, Dahl-Jorgensen K, Kiess W(Hrsg.): Diabetes mellitus in childhood and adolescence., Karger Verlag, Basel (2005); 181-189,ISBN 3-8055-7766-4

Raile K, Kapellen TM, Kiess W: Diabetes mellitus (pädiatrisch). in: Ber M, Domschke W, Hohenberger W, Meinertz T et al(Hrsg.): Therapiehandbuch. (Sonderdruck), Urban & Fischer, Elsevier, München (2005); 15-27,ISBN , 4. Auflage.  

Raile K, Kapellen T, Kiess W. Diabetes mellitus im Kindes- und Jugendalter In: Diabetes in der Praxis W. Waldhäusel, FA Griess und W Scherbaum (Hrgsb), 3. Auflage, Springer Verlag Berlin (2003); S 117-133 ISBN: 3–54040819–3. 

Kiess W, Raile K, Kapellen T, Pfaeffle R, Keller E, Blüher S, Böttner A. Multidisciplinary management of obesity in children and adolescents – why and how should it be achieved? S. 194-206, In: Kiess W, Marcus C, Wabitsch M, (eds.), Obesity in childhood and adolescence. Pediatr Adolesc Med. Basel, Karger Vol. 9 (2004) ISBN 3-8055-7730-3

Blüher S, Kiess W, Böttner A, Raile K, Kapellen T, Blüher M. Type 2 diabetes mellitus in children and adolescents, S. 170-180, In: Kiess W, Marcus C, Wabitsch M, (eds.), Obesity in childhood and adolescence. Pediatr Adolesc Med. Basel, Karger Vol. 9 (2004) ISBN 3-8055-7730-3.

Kiess W,  Klammt J, Bertholdt A, Raile K, Schmidt A, Seidel B, Kratzsch J: Regulation des intrauterinen Wachstums und endokrine Besonderheiten bei Frühgeborenen mit intrauteriner Wachstumsretardierung. in: Gortner, L.; Dudenhausen, J. W. (Hrsg.): Vorgeburtliches Wachstum und gesundheitliches Schicksal. Medizinische Verlagsanstalt Umwelt und Medizin Frankfurt (2001), S. 51 – 58, ISBN: 3-921320-56-9

Kiess W, Klammt J, Raile K, Schmidt A, Kratzsch J: Physiologische Wirkungen von GH/ IGF-1. in: Wüster Ch (Hrsg.): Wachstumshormon (hGH) – Pathophysiologie und therapeutisches Potential. Uni-Med Verlag Bremen 2001, S.21 – 26 ISBN: 3-89599-568-1. 

Raile K. Diabetes und Sport bei Kindern und Jugendlichen. in: Thurm, U.; Gehr, B. (Hrsg.): Diabetes- und Sportfibel. Kirchheim Verlag Mainz, 2001, S. 153 – 164 ISBN: 3-87409-338-7.

Herausgegebene Bücher

Edukids Arbeitsbuch für Eltern und Jugendliche Das Arbeitsbuch für die erste Diabetes-Schulung für Eltern und Jugendliche mit Diabetes mellitus Typ-1 im Rahmen der stationären Betreuung. Autoren: Karina Boss. Hrsg. Klemens Raile; 1.Auflage 2/2021.

Edukids Arbeitsbuch: Das Schulungsprogramm für pädagogische Fachkräfte, die Kinder mit Diabetes Typ 1 in der Schule betreuen. Hrsg. Edukids-Projektgruppe Karina Boss, Michaela Heinrich-Rohr, Romina Geissler, Klemens Raile Epubli, 28.8.2016; ISBN-13 978-3741843921 
 

• Berliner Gesellschaft für Kinder und Jugendmedizin (1.Vorsitzender)
• Verband leitender Klinikärzte (VLK) 
•  Deutsche Gesellschaft für Kinderheilkunde (DGKJ)
• Deutsche Diabetes Gesellschaft (DDG)
• Arbeitsgemeinschaft pädiatrische Diabetologie (AGPD)
• European Society for Paediatric Endocrinology (ESPE)
• International Society for Pediatric and Adolescent Diabetes (ISPAD)
• Deutsche Gesellschaft für päd. Endokrinologie und Diabetes (DGKED) 
• German Alliance for Global Health Research
• Verbändeübergreifenden Arbeitsgruppe DRG der GKinD e.V.
• Prüfungskommission des IMPP (Institut für medizinische und pharmazeutische Prüfungsfragen)